January 6, 2008

New Citations

1. High resolution HLA Typing - An analysis of the significance of high resolution typing in improving clinical outcome of unrelated UCB transplants reveals no discernable benefit, in agreement with some other reports. See Topic IX. HLA Matching, Citation #1.

2. Data on TNC recovery following processing cord blood units prior to cryopreservation using RBC reduction vs plasma reduction; also, comparison of washed units vs. unwashed units following thawing.
See Topic XXI CB Banking, section iv. Processing, cryopreservation and infusion, Citation #1 and Citation #2

3. Different outcomes in chemo-naïve patients vs more heavily treated patients following reduced intensity UCBT in children and adolescent patients. See Topic IV. Reduced intensity and non-myeloablative transplants, Citation #2

4. Are PBSC transplants losing some of their luster? A report of worse outcome and more cGVHD with PBSC transplants than with marrow transplants. [Is CB transplantation the solution to this problem?] See Topic VIII. GVHD, section i GVHD in BMT and PBSC transplants, Citation #1

5. Three significant publications on Immune Reconstitution following UCBT. See Topic XIII. Immune Reconstitution, Citation #1, Citation #2 and Citation #4