December 3, 2007
New Citations
1. Important Recent Data on GVHD See Citations in Topic VIII. GVHD
• A higher response rate to treatment of chronic GVHD in unrelated UCB transplants vs. adult unrelated donor (URD) transplants.
• Management of aGVHD (2007 Review Article)
• Management and outcome of cGVHD (2007 Review Article)
• Extracorporeal photochemotherapy for treatment of steroid-resistant cGVHD
• Two articles on the use of rituximab for treatment of steroid-refractory cGVHD
• Use of progenitor cells trapped in marrow filters to reduce GVHD and transplant mortality.
• Also, a list of reviews published in 2006 on the clinical spectrum and treatment of acute and chronic GVHD.
2. Are 2 cords better than 1? A commentary on an article by Brunstein et al: “Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplant outcomes in 110 adults with hematological disease” which is also posted in Topic IV, Reduced Intensity and Non-Myeloablative Transplants, i. Cord Blood Transplants (Citation #3). See the same section, Citation #4
3. Reduced intensity (RI) transplants
• Is there an upper age limit for HSCT?
• Immune reconstitution after RI regimens - a debated issue. See Reduced Intensity and Non-Myeloablative Transplants, ii. Marrow & PBSC Transplants, Citation #1
4. UCB in children with leukemia
A commentary on an article by Eapen et al.: “Outcomes of transplantation of unrelated donor umbilical cord blood and bone marrow in children with acute leukemia: a comparison study” which is also posted in Topic VII. Cord blood Transplantation in Children, i. Malignant disorders (Citation #1). See the same section, Citation #2
5. UCB in children with congenital disorders See Topic VII. Cord blood transplanataion in children, ii. congenital disorders, Citations #1-3, which includes:
• Trends in HSCT for inborn errors of metabolism.
• UCBT in Fanconi anemia patients.
• Correction of immunodeficiency associated with NEMO mutation by UCBT.
• Submyeloablative CBT for IPEX syndrome.
6. American Society of Hematolgy Meeting - a list of abstracts pertinent to cord blood transplantation
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