April 19, 2009
In Category II, Transplantation of Adults Using Cord Blood Units, Citations 1 & 2
- New data on outcomes after reduced-intensity UCB transplantation for adult hematologic malignancies. [“Older age per se cannot be considered to be a contraindication to RI-UCBT.”]
Prolonged survival in adults with acute lymphoblastic leukemia after reduced-intensity conditioning with cord blood or sibling donor transplantation. Bachanova et al. Blood 2009;113:2902-5.
Promising progression-free survival for patients low and intermediate grade lymphoid malignancies after nonmyeloablative umbilical cord blood transplantation. Brunstein et al. Biol Blood Marrow Transplant. 2009;15:214-222.
In Category VIII. Graft-Versus-Host Disease, Citation 6
- A report of effectiveness of rituximab for acute GVHD.
Rituximab reduces the incidence of acute graft-versus-host disease. Christopeit et al. Blood. 2009 26;113:3130-3131.
In Category XII. Sickle Cell Disease and Thalassemia i. Sickle Cell Disease, D. Umbilical Cord Blood Transplantation, Citation 1
- A detailed and authoritative review that discusses the successes, challenges and future direction of HCT for sickle cell disease (SCD) and thalassemia:
Recent advances in bone marrow transplantation in hemoglobinopathies. Michlitsch JG, Walters MC. Curr Mol Med. 2008;8:675-689