For those transplant physicians who are not familiar with cord blood transplantation and who would like to quickly review the field, the Forum recommends the following:

  1. The November 25, 2004 issue of the New England Journal of Medicine (Two articles on umbilical cord blood transplantation for adults and an editorial). In the Annotated Bibliography, these articles are reviewed in II. Transplantation of Adults using Cord Blood Units. Click HERE.

  2. Information on the effectiveness of double cord blood transplants in adults, see the following article: "Transplantation of two partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy." Barker et al. Blood 2005;105:1343-1347. This article is reviewed in III. Multi-Cord Transplants. Click HERE.

  3. For a recent comprehensive review, see "Umbilical cord blood transplantation." Rocha et al. Curr Opin Hematol. 2004;11:375-85 This article is reviewed in I. Recent Reviews (citation #2). Click HERE.

As all transplant physicians recognize, each year there are thousands of patients in need of a hematopoietic cell transplant who cannot find a suitable donor from among family members or from donor registries such as the NMDP. Can cord blood transplants, which do not require as precise an HLA match, satisfy that need for adults as well as children? Should cord blood transplants be more widely utilized? Among the alternative options is to not provide transplants even for patients with bona fide indications. The optimal way to decide is to review existing data, and the goal of this web site is to point to the availability of such information with an annotated bibliography, and to continually up-date the site as more pertinent publications become available.

Simply click on any of the topics listed below to see an annotated bibliography of recent data pertinent to that topic, or scroll down on the Annotated Bibliography page to review the entire bibliography. You may also search for any topic and/or author by clicking on the SEARCH link in the navigation menu to access our comprehensive site search feature. Among the critical topics are: Reviews, Transplantation of Adults, Multi-Cord Transplants, Cell dose, Availability and Rapidity of Obtaining of Cord Blood Units, GVHD, and HLA-matching

Please note that a link to an online abstract or full text version of each article is provided, if publicly available. Individuals with subscriptions to the journal may have online access to full text articles with a member sign-in on the journal's website. ASH members have online access to all full text articles published in Blood (initial sign-in required).

CordBloodForum.org would appreciate comments and questions.

0. THE TOP TEN
I. RECENT REVIEWS
II. TRANSPLANTATION OF ADULTS
III. MULTI-CORD TRANSPLANTS
IV. REDUCED INTENSITY AND NON-MYELOABLATIVE TRANSPLANTS
i. CORD BLOOD TRANSPLANTS
ii. MARROW AND PBSC TRANSPLANTS
V. DONOR SELECTION FOR UNRELATED CORD BLOOD TRANSPLANTATION
VI. AVAILABILITY AND TIME REQUIRED TO OBTAIN CORD BLOOD VERSUS BONE MARROW
VII. CORD BLOOD TRANSPLANTATION IN CHILDREN
i. MALIGNANT DISORDERS
ii. CONGENITAL DISORDERS
iii. ACQUIRED NON-MALIGNANT DISORDERS
VIII. GRAFT-VERSUS HOST DISEASE (GVHD)
i. GVHD IN BMT AND PBSC HEMATOPOIETIC CELL TRANSPLANTS
IX. HLA MATCHING
X. GRAFT-VERSUS-LEUKEMIA (GVL) ACTIVITY
XI. RECENT CORD BLOOD TRANSPLANTATION CONFERENCES
XII. SICKLE CELL DISEASE AND THALASSEMIA
i. SICKLE CELL DISEASE
A. CLINICAL ASPECTS
B. NEUROLOGIC COMPLICATIONS
C. BONE MARROW AND PBSC TRANSPLANTATION
D. UMBILICAL CORD BLOOD TRANSPLANTATION
ii. THALASSEMIA
A. CLINICAL ASPECTS
B. BONE MARROW AND PBSC TRANSPLANTATION
C. UMBILICAL CORD BLOOD TRANSPLANTATION
D. IRON OVERLOAD AND CHELATION
XIII. IMMUNE RECONSTITUTION
XIV. ADVERSE EVENTS IN CORD BLOOD TRANSPLANTATION
i.
INFECTIONS (OTHER THAN EBV)
ii.
EBV INFECTIONS / POST TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (PTLD)
iii.
IMMUNE CYTOPENIA
iv.
DONOR-DERIVED LEUKEMIA
v.
MISCELLANEOUS
XV. NEW CONCEPTS IN CORD BLOOD TRANSPLANTATION
i.
ADOPTIVE IMMUNOTHERAPY AFTER CBT
ii.
CO-TRANSPLANTATION OF CORD BLOOD UNITS AND MOBILIZED STEM CELLS FROM A THIRD PARTY DONOR
iii.
PREIMPLANTATION GENETIC DIAGNOSIS
iv.
IN-VIVO EXPANSION OF CORD BLOOD STEM CELLS
v.
SERIAL TRANSPLANTATION RESULTING IN TOLERANCE
XVI. STEM CELL PLASTICITY AND REGENERATIVE MEDICINE
XVII. RELATED CORD BLOOD TRANSPLANTATION
XVIII. EX-VIVO EXPANSION OF HEMATOPOIETIC PROGENITOR CELLS
XIX. MISCELLANEOUS TOPICS
i.
MESENCHYMAL STEM CELLS
ii.
GRANULOCYTE TRANSFUSION
iii.
REGULATORY ISSUES
iv.
AUTOIMMUNE DISEASES
v.
HIV POSITIVE PATIENTS
vi.
ACUTE RADIATION INJURY
vii.
OTHER ITEMS
XX. ARTICLES REGARDING BMT AND/OR PBSC WITH RELEVANCE TO CORD BLOOD TRANSPLANTATION
XXI. CORD BLOOD BANKING
i. OVERVIEW
ii. INFORMED CONSENT
iii. STRATEGIES FOR CORD BLOOD COLLECTION
iv. PROCESSING, CYROPRESERVATION AND INFUSION
v. QUALITY ISSUES
XXII. BOOKS
XXIII. AMERICAN SOCIETY OF HEMATOLOGY (ASH) ABSTRACTS 2007

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Page Updated
30 April 2008
Disclaimer: The Cord Blood Forum endorses collegial discussion among cord blood transplantation professionals, patients and donors. However, the Cord Blood Forum does not necessarily endorse, nor take any responsibility for the specific views and opinions expressed in the forum. The forum is not intended as a substitute for legal and/or medical advice and the content should not be relied upon for medical and/or legal purposes. Readers should make their own determinations as to: (i) what constitutes appropriate medical, technical, and administrative practices, and (ii) how best to comply with laws and regulations relevant to their questions. For the latter, they should consider consulting with an attorney familiar with related state and federal laws.

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