A continuously changing selection of articles

I. Recent Reviews

Citation #1. Umbilical Cord Blood (UCB) Transplantation: An Alternative to the Use of Unrelated Volunteer Donors? Barker JN Hematology Am Soc Hematol Educ Program. 2007;2007:55-61.

Citation #2. Expanding the role of umbilical cord blood transplantation. Brunstein CG, Setubal DC, Wagner JE. Br J Haematol. 2007;137:20-35.

II. Transpantation of Adults using Cord Blood Units

Citation #1. Cord blood transplantation for adults. Brunstein CG, Wagner JE. Brunstein G, Wagner JE. Vox Sang. 2006;91:195-205.

III. Multi-Cord Transplants

Citation #2. Double umbilical cord blood transplantation. Majhail NS, Brunstein CG, Wagner JE. Curr Opin Immunol. 2006; 18: 1-5.

Citation #1. Umbilical cord blood transplantation after nonmyeloablative conditioning: impact on transplant outcomes in 110 adults with hematological disease. Brunstein CG, Barker JN, Weisdorf DJ, Defor TE, Miller JS, Blazar BR, McGlave PB, Wagner JE. Blood. 2007;110:3064-3070.

IV. Reduced Intensity and Non-Myeloablative Transplants

Citation #1. Reduced-intensity allogeneic transplant in patients older than 55 years: unrelated umbilical cord blood is safe and effective for patients without a matched related donor. Majhail NS, Brunstein CG, Tomblyn M, Thomas AJ, Miller JS, Arora M, Kaufman DS, Burns LJ, Slungaard A, McGlave PB, Wagner JE, Weisdorf DJ. Biol Blood Marrow Transplant. 2008;14:282-9.

V. Donor Selection for Unrelated Cord Blood Transplantation

Citation #1. Donor selection for unrelated cord blood transplants. Gluckman E, Rocha V. Curr Opin Immunol. 2006; 18:565-70

VIII. Graft-Versus-Host Disease

Citation #1. Chronic graft-versus-host disease (cGVHD) following unrelated donor hematopoietic stem cell transplantation (HSCT): higher response rate in recipients of unrelated donor (URD) umbilical cord blood (UCB). Arora M, Nagaraj S, Wagner JE, Barker JN, Brunstein CG, Burns LJ, Defor TE, McMillan ML, Miller JS, Weisdorf DJ. Biol Blood Marrow Transplant. 2007;13:1145-52.

[NOTE: These citations are among a plethora of articles that continue to emerge indicating that GVHD, especially extensive chronic GVHD, is significantly more frequent after PBSC and less easily treated than after cord blood transplants. Although PBSC grafts provide a number of advantages, the high rate of GVHD, especially chronic GVHD, is of such serious concern as to suggest re-consideration of this source of stem cells for HSCT. For further details concerning this important point see: Annotated Bibliography VIII, Graft-versus Host Disease, i Graft versus host disease in BMT and PBSC hematopoietic cell transplants, citations #1, 11, 12, 15 and 16.]

IX. HLA Matching

Citation #2. Hematopoietic stem cell donor selection: the Europdonor experience. Oudshoorn M, van Walraven SM, Bakker JN, Lie JL, V D Zanden HG, Heemskerk MB, Claas FH. Hum Immunol. 2006; 67:405-412.

Citation #1. Indiscernible benefit of high-resolution HLA typing in improving long-term clinical outcome of unrelated umbilical cord blood transplant. Liao C, Wu JY, Xu ZP, Li Y, Yang X, Chen JS, Tang XW, Gu SL, Huang YN, Tang PH, Tsang KS. Bone Marrow Transplant. 2007;40:201-208.